For patients with hypoxemia, dyspnea, or pneumonia, simple oxygen therapy alone may not effectively alleviate inflammatory responses or breathing difficulties. Combining aerosolized medication nebulization with oxygen humidification can promote pulmonary ventilation, improve secretion clearance, and relieve symptoms. This strategy is widely applied in chronic obstructive pulmonary disease (COPD), long-term oxygen therapy patients, postoperative care, acute and chronic respiratory infections, and post-COVID-19 rehabilitation stages. It achieves synergistic effects of oxygen supplementation combined with bronchodilators or saline nebulization, enhancing overall respiratory function and patient comfort.